Synthesis of highly functionalised dibenzylglycine derivatives via the Suzuki–Miyaura coupling reaction

Several α,α-dibenzylglycine (α-benzylphenylalanine) derivatives were prepared by alkylation of the ethyl isocyanoacetate with different benzyl bromide derivatives. Various aryl groups were introduced in the dibenzylglycine moiety via the Suzuki–Miyaura coupling reaction.