Title of article
Biotinylated lithocholic acids for affinity chromatography of mammalian DNA polymerases α and β
Author/Authors
Madoka Watanabe، نويسنده , , Shinya Hanashima، نويسنده , , Yoshiyuki Mizushina، نويسنده , , Hiromi Yoshida، نويسنده , , Masahiko Oshige، نويسنده , , Kengo Sakaguchi، نويسنده , , Fumio Sugawara، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
287
To page
290
Abstract
Biotinylated lithocholic acids have been synthesized. The compounds inhibited mammalian DNA polymerases α and β with dose-dependent manner. The streptavidine columns conjugated with the synthetic biotinylated compounds chromatographed both two enzymes eluted by KCl solution at the different concentrations.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
791955
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