Author/Authors :
Ken-ichi Nihei، نويسنده , , Massuo J. Kato، نويسنده , , Tetsuo Yamane، نويسنده , , Mario S. Palma، نويسنده , , Katsuhiro Konno، نويسنده ,
Abstract :
An efficient and versatile synthesis of acylpolyamine spider toxins was developed based on the structural classification of the Nephila and Nephilengys spider toxins using the 2-nitrobenzenesulfonamide protecting group. The naturally occurring toxins 1–5 representing each structural type have been efficiently synthesized by this method in a high overall yield with few steps.
