Title of article :
Binding of Aminoglycoside Antibiotics with Modified A-site 16S rRNA Construct Containing Non-Nucleotide Linkers
Author/Authors :
Jeffrey B. -H. Tok، نويسنده , , Wilson Wong، نويسنده , , Nyla Baboolal، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
The design and synthesis of synthetically modified cyclic A-site 16S rRNA construct is reported. The binding characteristics of several members of the aminoglycoside antibiotics with this novel class of synthetically modified A-site 16S rRNA constructs were subsequently investigated.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters