Title of article
Absorption Studies on Aminoglycoside Binding to the Packaging Region of Human Immunodeficiency Virus Type-1
Author/Authors
Julie M. Sullivan، نويسنده , , Jerry Goodisman، نويسنده , , James C. Dabrowiak، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
615
To page
618
Abstract
The binding of paromomycin, neomycin B, and three analogues of neomycin to a 176-mer RNA from the packaging region of HIV-1 (LAI) has been studied using UV absorption spectroscopy at wavelengths between 200 and 300 nm. From plots of absorption as a function of drug concentration, values of binding constants for these drugs on RNA were determined.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792030
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