Title of article :
β-Carboline–Carbohydrate hybrids: molecular design, chemical synthesis and evaluation of novel DNA photocleavers
Author/Authors :
Kazunobu Toshima، نويسنده , , Yukiko Okuno، نويسنده , , Yoko Nakajima، نويسنده , , Shuichi Matsumura، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
β-Carboline present in β-carboline alkaloids from marine organisms was found, for the first time, to cleave DNA at the guanine site upon irradiation with UV light with a long wavelength without any additive, and β-carboline–carbohydrate hybrid system was effective for DNA cleavage.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
