Title of article
An additional 2′-ribofuranose residue at a specific position of the DNA primer prevents Its elongation by HIV-1 reverse transcriptase
Author/Authors
O. I. Andreeva، نويسنده , , A. S. Golubeva، نويسنده , , S. N. Kochetkov، نويسنده , , A. Van Aerschot، نويسنده , , P. Herdewijn، نويسنده , , E. V. Efimtseva، نويسنده , , B. S. Ermolinsky، نويسنده , , S. N. Mikhailov، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
681
To page
684
Abstract
Oligodeoxynucleotides containing 2′-O-β- -ribofuranosyladenosine were prepared and used as modified primers in RNA-templated DNA synthesis catalyzed by HIV reverse transcriptase. It was shown that the additional 2′-ribofuranose residue in specific position of primer prevents its elongation.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792046
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