Title of article
Oxime derivatives of sordaricin as potent antifungal agents
Author/Authors
Michael H. Serrano-Wu، نويسنده , , Denis R. St. Laurent، نويسنده , , Charles E. Mazzucco، نويسنده , , Terry M. Stickle، نويسنده , , John F. Barrett، نويسنده , , Dolatrai M. Vyas، نويسنده , , Balu N. Balasubramanian، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
943
To page
946
Abstract
Oxime derivatives of the sordarin aglycone have been identified as potent antifungal agents. The in vitro spectrum of activity includes coverage against Candida albicans and Candida glabrata with MICs as low as 0.06 μg/mL. The antifungal activity was established to be exquisitely sensitive to the spatial orientation of the lipophilic side chains.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792106
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