Title of article :
Benzimidazole-4,7-diones as Inhibitors of Protozoal (Toxoplasma gondii) Purine Nucleoside Phosphorylase
Author/Authors :
Frédéric Alvarez، نويسنده , , Arnaud Ghérardi، نويسنده , , Pascal Nebois، نويسنده , , Marie-Elizabeth Sarciron، نويسنده , , Anne-Françoise Pétavy، نويسنده , , Nadia Walchshofer، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
Benzimidazole-4,7-diones derivatives substituted at 1- and/or 2-position have been synthetized and tested as inhibitors of purine nucleoside phosphorylase (PNP), isolated from two strains of Toxoplasma gondii (RH and ME 49). They were identified as inhibitors of both enzymes.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
