Title of article :
Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 1: Structure-based design of novel acetylenic P1′ groups
Author/Authors :
James M. Chen، نويسنده , , Guixian Jin، نويسنده , , Amy Sung، نويسنده , , Jeremy I. Levin، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
The structure-based design of potent sulfonamide hydroxamate TACE inhibitors bearing novel acetylenic P1′ groups has led to compounds with excellent in vitro potency against TACE and selectivity over MMP-1.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
