Title of article
Novel lipoic acid analogues that inhibit nitric oxide synthase
Author/Authors
Jeremiah J. Harnett، نويسنده , , Michel Auguet، نويسنده , , Isabelle Viossat، نويسنده , , Christine Dolo، نويسنده , , Dennis Bigg، نويسنده , , Pierre-E. Chabrier، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
1439
To page
1442
Abstract
The synthesis and biological activity of novel lipoic acid analogues are reported. Lipoic acid and structural homologues coupled to arylthiophene amidine via carboxamide linkers are metabolic antioxidants capable of protecting neuronal cells against glutamate cytotoxicity, preventing loss of intracellular glutathione, and inhibit nitric oxide synthase.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792232
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