Title of article
Synthesis of novel furo, thieno, and benzazetoazepines and evaluation of their cytotoxicity
Author/Authors
L. Roberto Mart?nez، نويسنده , , Jose Gustavo Avila Zarraga، نويسنده , , M Esther Duran، نويسنده , , M Teresa Ram?rez Apam، نويسنده , , Roberto Ca?as، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
1675
To page
1677
Abstract
We report the regio- and stereoselective synthesis of a novel cis-C3N-C4X-C6N series (X=O, S, and C2) from cyclic ketones. The cytotoxic activity of the new compounds was studied in five cell lines; the observed activities were in accordance with the concept of bioisosteric replacement.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792286
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