• Title of article

    Discovery of potent and selective small molecule NPY Y5 receptor antagonists

  • Author/Authors

    Imadul Islam، نويسنده , , Dale Dhanoa، نويسنده , , John Finn، نويسنده , , Ping Du، نويسنده , , Mary W. Walker، نويسنده , , John A. Salon، نويسنده , , Jack Zhang، نويسنده , , Charles Gluchowski، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    1767
  • To page
    1769
  • Abstract
    The discovery of a new class of sulfonamide NPY Y5 receptor antagonists is described. Optimization of this series led to the identification of compounds with high affinity for the hY5 subtype and excellent selectivity over the other NPY receptor subtypes. The SAR for this series was examined and a model for understanding the ligand–receptor interactions was developed.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792309

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=792309