Title of article
Design and synthesis of novel inhibitors of gelatinase B
Author/Authors
Xueqing Wang، نويسنده , , Youngchool Choe، نويسنده , , Charles S. Craik، نويسنده , , Jonathan A. Ellman، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
2201
To page
2204
Abstract
A new method was developed to identify nonpeptidic metalloproteinase inhibitors with novel zinc binding groups. Application of this method to matrix metalloproteinase-9 resulted in the identification of aminomethyl benzimidazole analogue 7a with an IC50=13 μM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792408
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