Title of article :
A Practical Synthesis of 3,4-Diethoxybenzthioamide Based on Friedel–Crafts Reaction with Potassium Thiocyanate in Methanesulfonic Acid
Author/Authors :
Shinji Aki، نويسنده , , Takafumi Fujioka، نويسنده , , Masashi Ishigami، نويسنده , , Jun-ichi Minamikawa، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
The synthesis of 3,4-diethoxybenzthioamide, the key intermediate for OPC-6535, is achieved by employing Friedel–Crafts reaction of 1,2-diethoxybenzene with potassium thiocyanate in methanesulfonic acid at ambient temperature.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
