Quaternary Salts of E2020 Analogues as Acetylcholinesterase Inhibitors for the Reversal of Neuromuscular Block
Author/Authors :
John K. Clark، نويسنده , , Phill Cowley، نويسنده , , Alan W. Muir، نويسنده , , Ronald Palin، نويسنده , , Eleanor Pow، نويسنده , , Alan B. Prosser، نويسنده , , Robert Taylor، نويسنده , , Mingqiang Zhang، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
4
From page :
2565
To page :
2568
Abstract :
A series benzylpiperidinium and benzylpyridinium quaternary salts have been synthesised and tested for inhibition of acetylcholinesterase and reversal of neuromuscular block induced by vecuronium. Several potent reversal agents have been identified and their haemodynamic effects measured.