Title of article
DNA Binding Ligands with Excellent Antibiotic Potency Against Drug-Resistant Gram-Positive Bacteria
Author/Authors
Roland W. Bürli، نويسنده , , Yigong Ge، نويسنده , , Sarah White، نويسنده , , Eldon E. Baird، نويسنده , , Sofia M. Touami، نويسنده , , Matthew Taylor، نويسنده , , Jacob A. Kaizerman، نويسنده , , Heinz E. Moser، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
2591
To page
2594
Abstract
An efficient synthesis of DNA binding molecules consisting of four heterocyclic carboxamide units and various substituents at both termini is described. The minor-groove binding ligands showed excellent activity against a broad range of Gram-positive bacteria; no cross-resistance to known antibacterial drugs was observed.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792502
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