Title of article :
4-Aminoquinolines as a novel class of NR1/2B subtype selective NMDA receptor antagonists
Author/Authors :
Emmanuel Pinard، نويسنده , , Alexander Alanine، نويسنده , , Anne Bourson، نويسنده , , Bernd Büttelmann، نويسنده , , Marie-Paule Heitz، نويسنده , , Vincent Mutel Ramanjit Gill، نويسنده , , Gerhard Trube، نويسنده , , René Wyler، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Pages :
5
From page :
2615
To page :
2619
Abstract :
Screening of the Roche compound library led to the identification of 4-aminoquinoline 4 as structurally novel NR1/2B subtype selective NMDA receptor antagonist. The SAR which was developed in this series resulted in the discovery of highly potent and in vivo active blockers.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Serial Year :
2002
Journal title :
Bioorganic & Medicinal Chemistry Letters
Record number :
792508
Link To Document :
بازگشت