Title of article
2,5-Pyridinedicarboxylic acid derivatives as non-Nucleosidic Reverse transcriptase inhibitors of Hepatitis B Virus
Author/Authors
Jinsoo Lee، نويسنده , , HyungSoo Shim، نويسنده , , YongKyun Park، نويسنده , , SangJin Park، نويسنده , , JoonSu Shin، نويسنده , , WangYong Yang، نويسنده , , HakDong Lee، نويسنده , , WhuiJung Park، نويسنده , , YongHo Chung، نويسنده , , Sangwook Lee، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
2715
To page
2717
Abstract
2,5-Pyridinedicarboxylic acid derivatives were found to be the potent non-nucleoside inhibitors of hepatitis B virus (HBV) with IC50 ≤0.01 μg/mL in a reverse transcriptase inhibitory effect. And they showed the low toxicity compared with the nucleoside analogues.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792527
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