Title of article
Synthesis and mannose receptor-Mediated uptake of clustered glycomimetics by human dendritic cells: effect of charge
Author/Authors
Gerhild Angyalosi، نويسنده , , Cyrille Grandjean، نويسنده , , Mélanie Lamirand، نويسنده , , Claude Auriault، نويسنده , , Hélène Gras-Masse، نويسنده , , Oleg Melnyk، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
5
From page
2723
To page
2727
Abstract
Effect of charge and shape of multivalent lysine-based cluster glycomimetics on their mannose receptor-mediated uptake by human dendritic cells has been evaluated: The capture is strongly affected by the shape of the ligands. The effect of charge is less pronounced although positive charges on the ligands seem to favor non-specific endocytosis capture.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792529
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