Title of article
Synthesis and evaluation of novel pyrrolidinyl sordaricin derivatives as antifungal agents
Author/Authors
Masami Arai، نويسنده , , Tamako Harasaki، نويسنده , , Takashi Fukuoka، نويسنده , , Satoru Kaneko، نويسنده , , Toshiyuki Konosu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
2733
To page
2736
Abstract
N-Benzyl pyrrolidinyl sordaricin derivatives have been synthesized from cis-4-hydroxy- -proline in a stereocontrolled manner. These compounds maintained moderate antifungal activity against several pathogenic fungal strains. Their MIC values against Candida albicans were in the range of 0.25–2 μg/mL.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792531
Link To Document