Synthesis of poly(maleimide-co-2-ethylacrylic acid) and its properties of suppressing metastasis and growth of carcinoma

A series of copolymers is prepared using maleimide and 2-ethylacrylic acid as comonomer. This kind of copolymer shows low toxicity (LD50: 601–798 mg/kg) and significant curative effect on Lewis lung carcinoma and S180.