Title of article
Novel lopinavir analogues incorporating non-Aromatic P-1 side chains—Synthesis and structure–Activity relationships
Author/Authors
Hing L. Sham، نويسنده , , Chen Zhao، نويسنده , , Leping Li، نويسنده , , David A. Betebenner، نويسنده , , Ayda Saldivar، نويسنده , , Sudthida Vasavanonda، نويسنده , , Dale J. Kempf، نويسنده , , Jacob J. Plattner، نويسنده , , Daniel W. Norbeck، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
3101
To page
3103
Abstract
The HIV protease inhibitor Lopinavir has a pseudosymmetric core unit incorporating benzyl groups at both P-1, P-1′ positions. A series of analogues incorporating non-aromatic side chains at the P-1 position were synthesized and the structure–activity relationships explored.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792609
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