Title of article
A survey of cyclic replacements for the central diamide moiety of inhibitors of inosine monophosphate dehydrogenase
Author/Authors
T. G. Murali Dhar، نويسنده , , Chunjian Liu، نويسنده , , William J. Pitts، نويسنده , , Junquing Guo، نويسنده , , Scott H. Watterson، نويسنده , , Henry Gu، نويسنده , , Catherine A. Fleener، نويسنده , , Katherine Rouleau، نويسنده , , N. Z. Sherbina، نويسنده , , Joel C. Barrish، نويسنده , , Diane Hollenbaugh، نويسنده , , Edwin J. Iwanowicz، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
4
From page
3125
To page
3128
Abstract
A series of heterocyclic replacements for the central diamide moiety of 1, a potent small molecule inhibitor of inosine monophosphate dehydrogenase (IMPDH) were explored The synthesis and the structure–activity relationships (SARs), derived from in vitro studies, for these new series of inhibitors is given.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792614
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