Title of article :
DNA Interaction and photonicking properties of DNA-Targeted acridine (2,2′-Bipyridine)Platinum(II) complexes
Author/Authors :
Lourdes Gude، نويسنده , , Mar?a-José Fern?ndez، نويسنده , , Kathryn B. Grant، نويسنده , , Antonio Lorente، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2002
Abstract :
Synthesis of two (2,2′-bipyridine)platinum(II) complexes tethered to one or two acridine chromophores is reported. These acridine complexes efficiently unwind and photocleave supercoiled plasmid DNA under physiological conditions of temperature and pH.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters
