• Title of article

    Benzotrithiole 2-oxide: A new family of thiol-Activated DNA-Cleaving functionalities

  • Author/Authors

    Alex H. F. Lee، نويسنده , , Albert S. C. Chan، نويسنده , , Tianhu Li، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    3
  • From page
    3259
  • To page
    3261
  • Abstract
    It was demonstrated in our studies that benzotrithiole 2-oxide was capable of causing efficient DNA cleavage in the presence of 2-mercaptoethanol or glutathione and exhibited potent cytotoxic properties against certain cancer cell lines.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2002
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    792645