Title of article :
Structure–activity relationships for a series of thiobenzamide influenza fusion inhibitors derived from 1,3,3-Trimethyl-5-hydroxy-cyclohexylmethylamine
Author/Authors :
Kuo-Long Yu، نويسنده , , Albert F. Torri، نويسنده , , Guangxiang Luo، نويسنده , , Christopher Cianci، نويسنده , , Katharine Grant-Young، نويسنده , , Stephanie Danetz، نويسنده , , Lawrence Tiley، نويسنده , , Mark Krystal، نويسنده , , Nicholas A. Meanwell، نويسنده ,
Abstract :
The anti-influenza activity of a series of thiobenzamide fusion inhibitors derived from 1,3,3-trimethyl-5-hydroxy-cyclohexylmethylamine is profiled. Axial disposition of the thioamide moiety is essential for potent influenza inhibitory activity.
