Title of article
Synthesis and cytotoxic activity of a new potent daunomycinone derivative
Author/Authors
Nectarios Aligiannis، نويسنده , , Nicole Pouli، نويسنده , , Panagiotis Marakos، نويسنده , , Alexios-Leandros Skaltsounis، نويسنده , , Harris Pratsinis، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
3505
To page
3507
Abstract
The preparation and cytotoxic activity of 4′-azido-3′-bromo-3′-deamino-4′-deoxydaunorubicin is described. The new compound was found to be less active in vitro than adriamycin against L1210 and the sensitive cell lines KB-3-1 and MES-SA, but retained interesting cytotoxicity against the adriamycin resistant subline KB-A1 and the multidrug resistant MES-SA/Dx5 subline.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792701
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