Title of article
Synthesis and pharmacological evaluation of a new class of peroxisome proliferator-activated receptor modulators
Author/Authors
Markus Thor، نويسنده , , Katarina Beierlein، نويسنده , , Graeme Dykes، نويسنده , , Anna-Lena Gustavsson، نويسنده , , Jessica Heidrich، نويسنده , , Lena Jendeberg، نويسنده , , Bengt Lindqvist، نويسنده , , Cecile Pegurier، نويسنده , , Patrick Roussel، نويسنده , , Martin Slater، نويسنده , , Stefan Svensson، نويسنده , , Mona Sydow-B?ckman، نويسنده , , Ulla Thornstr?m، نويسنده , , Jonas Uppenberg، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
3
From page
3565
To page
3567
Abstract
A series of 5-substituted 2-benzoylaminobenzoic acids has been synthesized and assayed for PPARα/γ activity. Both dual activators and selective PPARγ agonists have been identified. This class of compounds was shown to activate the PPARγ receptor through interaction with a novel binding site.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2002
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792715
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