Author/Authors :
Young-Won Chin، نويسنده , , Song Won Lim، نويسنده , , Seok-Ho Kim، نويسنده , , Dong-Yun Shin، نويسنده , , Young-Ger Suh، نويسنده , , Yang-Bae Kim، نويسنده , , Young Choong Kim، نويسنده , , Jinwoong Kim، نويسنده ,
Abstract :
As a part of our search for hepatoprotective compounds from Lycium chinense fruits, three new pyrrole derivatives (1–3) were isolated. These compounds and a related synthetic methylated compound (4) were evaluated for their biological activity and structure–activity relationship, and compounds 1 and 2 showed hepatoprotective effects comparable to silybin at the concentration of 0.1 μM (64.4 and 65.8%, respectively).
