Title of article
Hepatoprotective pyrrole derivatives of Lycium chinense fruits
Author/Authors
Young-Won Chin، نويسنده , , Song Won Lim، نويسنده , , Seok-Ho Kim، نويسنده , , Dong-Yun Shin، نويسنده , , Young-Ger Suh، نويسنده , , Yang-Bae Kim، نويسنده , , Young Choong Kim، نويسنده , , Jinwoong Kim، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
79
To page
81
Abstract
As a part of our search for hepatoprotective compounds from Lycium chinense fruits, three new pyrrole derivatives (1–3) were isolated. These compounds and a related synthetic methylated compound (4) were evaluated for their biological activity and structure–activity relationship, and compounds 1 and 2 showed hepatoprotective effects comparable to silybin at the concentration of 0.1 μM (64.4 and 65.8%, respectively).
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792864
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