Title of article :
Dihydropyrimidinones—a new class of anti-Staphylococcal antibiotics
Author/Authors :
Michael Brands، نويسنده , , Rainer Endermann، نويسنده , , Reinhold Gahlmann، نويسنده , , Jochen Krüger، نويسنده , , Siegfried Raddatz، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Abstract :
We report the synthesis and pharmacological evaluation of new derivatives of natural dipeptide antibiotic TAN-1057 A, B. In the course of this program, we identified novel analogues of the natural product that display similar antibacterial activity and showed improved tolerability.
Journal title :
Bioorganic & Medicinal Chemistry Letters
Journal title :
Bioorganic & Medicinal Chemistry Letters