Title of article
CRF Ligands via suzuki and negishi couplings of 3-pyridyl boronic acids or halides with 2-benzyloxy-4-chloro-3-nitropyridine
Author/Authors
Argyrios G. Arvanitis، نويسنده , , Charles R. Arnold، نويسنده , , Lawrence W. Fitzgerald، نويسنده , , William E. Frietze، نويسنده , , Richard E. Olson، نويسنده , , Paul J. Gilligan، نويسنده , , David W. Robertson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
289
To page
291
Abstract
A series of imidazo[4,5-b]pyridines with a 7-(3-pyridyl) substituent is described as high affinity CRF receptor ligands. Individual analogues were synthesized from key intermediates obtained via palladium-catalyzed coupling of 3-pyridyl zinc or boronic acid organometallic intermediates with 2-benzyloxy-4-chloro-3-nitropyridine 12.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792909
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