Title of article
The synthesis of NPPB and NPBB by reductive amination and the effects of these compounds on K+ channels of the alga Nitella hookeri
Author/Authors
Kristian R. Giles، نويسنده , , Mark Humphries، نويسنده , , Andrew Abell، نويسنده , , Ashley Garrill، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
293
To page
295
Abstract
This paper communicates a new synthesis of the ion channel inhibitors NPPB and NPBB using a simple reductive amination sequence. The synthesised compounds were found to reduce channel amplitude of a K+ channel present in cytoplasmic droplets of Nitella hookeri.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792910
Link To Document