Title of article
Inhibition of inosine monophosphate dehydrogenase (IMPDH) by 2-[2-(Z)-Fluorovinyl]inosine 5′-Monophosphate
Author/Authors
Vasu Nair، نويسنده , , Ramesh C. Kamboj، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
645
To page
647
Abstract
Inosine 5′-monophosphate dehydrogenase (IMPDH; EC 1.1.1.205) isolated from Escherichia coli B3 cells was strongly inhibited by 2-[2-(Z)-fluorovinyl]inosine 5′-monophosphate (2-FVIMP). Inhibition of IMPDH appears to be irreversible with kinact and Ki values of 0.0269 s−1 and 1.11 μM, respectively.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
792984
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