Title of article
Design, synthesis, and structure–Activity relationships of substituted piperazinone-Based transition state factor Xa inhibitors
Author/Authors
Ting Su، نويسنده , , Hua Yang، نويسنده , , Deborah Volkots، نويسنده , , John Woolfrey، نويسنده , , Suiko Dam، نويسنده , , Paul Wong، نويسنده , , Uma Sinha، نويسنده , , Robert M. Scarborough، نويسنده , , Bing-Yan Zhu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
729
To page
732
Abstract
The structure–activity relationship of a novel series of substituted piperazinone-based factor Xa inhibitors is described. The most potent compound 34 displays IC50 of 0.9 nM.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793003
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