• Title of article

    Hydroporphyrins as tumour photosensitizers: synthesis and photophysical studies of 2,3-Dihydro-5,15-di(3,5-dihydroxyphenyl) porphyrin

  • Author/Authors

    Yann Ferrand، نويسنده , , Ludovic Bourré، نويسنده , , Gérard Simonneaux، نويسنده , , Sonia Thibaut، نويسنده , , Fabrice Odobel، نويسنده , , Y. Lajat، نويسنده , , Thierry Patrice، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2003
  • Pages
    3
  • From page
    833
  • To page
    835
  • Abstract
    The synthesis and characterization of 2,3-dihydro-5,15-di(3,5-dihydroxyphenyl) porphyrin is reported. The phototoxicity on C6 cell lines and the pharmacokinetics are also reported as preliminary results showing a very high tumor to skin ratio and short retention time in tissues, and thus promising activity in photodynamic therapy.
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Serial Year
    2003
  • Journal title
    Bioorganic & Medicinal Chemistry Letters
  • Record number

    793026