Title of article
Novel Openers of Ca2+-Dependent Large-Conductance Potassium Channels: Symmetrical Pharmacophore and Electrophysiological Evaluation of Bisphenols
Author/Authors
Yi Li، نويسنده , , Graham Johnson، نويسنده , , Jeffrey L. Romine، نويسنده , , Nicholas A. Meanwell، نويسنده , , Scott W. Martin، نويسنده , , Steven I. Dworetzky، نويسنده , , Christopher G. Boissard، نويسنده , , Valentin K. Gribkoff، نويسنده , , John E. Starrett Jr، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
1437
To page
1439
Abstract
Electrophysiological evaluation of symmetrical analogues of the known maxi-K opener NS-004 (1) led to the discovery of bisphenols 2a, 3a and 4a as openers of cloned maxi-K channels expressed in oocytes.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793158
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