Title of article
Discovery of 3-Amino-4-Chlorophenyl P1 as a novel and potent benzamidine mimic via solid-phase synthesis of an isoxazoline library
Author/Authors
Patrick Y. S. Lam، نويسنده , , Jessica J. Adams، نويسنده , , Charles G. Clark، نويسنده , , W. Jason Calhoun، نويسنده , , Joseph M. Luettgen، نويسنده , , Robert M. Knabb، نويسنده , , Ruth R. Wexler، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
5
From page
1795
To page
1799
Abstract
In an effort to identify orally bioavailable factor Xa inhibitors, two isoxazolines libraries were prepared to scan for novel P1 ligands. From this work, 4-chloro-3-aniline was identified as a novel and potent benzamidine mimic.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793237
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