Title of article
Synthesis, stereochemical assignment and biological activity of a novel series of C-4″ modified aza-Macrolides
Author/Authors
Brian S. Bronk، نويسنده , , Michael A. Letavic، نويسنده , , Camilla D. Bertsche، نويسنده , , David M. George، نويسنده , , Shigeru F. Hayashi، نويسنده , , Barbara J. Kamicker، نويسنده , , Nicole L. Kolosko، نويسنده , , Laura J. Norcia، نويسنده , , Margaret A. Rushing، نويسنده , , Sheryl L. Santoro، نويسنده , , Bingwei V. Yang، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
1955
To page
1958
Abstract
Modification of the cladinose C-4″ position via manipulation of the corresponding keto derivatives afforded two stereochemically pure series of compounds. The synthesis and structure determination of these compounds is described within. The in vitro and in vivo biological activity of this novel series of C-4″ modified macrolides is also described.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793273
Link To Document