Title of article
Cyclic amine sulfonamides as linkers in the design and synthesis of novel human β3 adrenergic receptor agonists
Author/Authors
Fuk-Wah Sum، نويسنده , , Victoria Wong، نويسنده , , Stella Han، نويسنده , , Elwood Largis، نويسنده , , Ruth Mulvey، نويسنده , , Jeff Tillett، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2191
To page
2194
Abstract
Piperidine, pyrrolidine, and azetidine sulfonamides were examined as linkers in designing novel human β3 adrenergic receptor (β3-AR) agonists. The azetidine derivative 37, and piperidine derivatives 7, 8, and 13 were found to be potent β3-AR agonists and have good selectivity against β1- and β2-AR.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793324
Link To Document