Author/Authors :
Hye Yeon Kim and Frederick T. Sheldon ، نويسنده , , Jae Seok Lee، نويسنده , , Joo Hwan Cha، نويسنده , , Ae Nim Pae، نويسنده , , Yong Seo Cho، نويسنده , , Moon Ho Chang، نويسنده , , Hun Yeong Koh، نويسنده ,
Abstract :
We have prepared and evaluated the antibacterial activities of a series of substituted methylenepiperidinyl and methylenepyrrolidinyl oxazolidinones against several gram-positive strains including the resistant strains of Staphyloccus and Enterococcus, such as MRSA, CRSA, MSSA and VRE. Some of them showed comparable or superior in vitro activities (MIC) to vancomycin.
