Title of article
Development of 3D-QSAR models in cyclic ureidobenzenesulfonamides: human β3-Adrenergic receptor agonist
Author/Authors
Sushil K. Kashaw، نويسنده , , Lalit Rathi، نويسنده , , Pradeep Mishra، نويسنده , , Anil K. Saxena، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2481
To page
2484
Abstract
Pharmacophoric mapping based on 3D-QSAR studies is performed on sixteen cyclic ureidobenzenesulfonamides for their β3-adrenergic receptor agonistic activity. The best 3D-QSAR model (with r2=0.877) which described the properties and distributions of 5-biophoric and 2-secondary biophoric sites, showed a good correlation between the observed and predicted activity both in training and test.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793381
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