Author/Authors :
Paola Barraja، نويسنده , , Patrizia Diana، نويسنده , , Antonino Lauria، نويسنده , , Alessandra Montalbano، نويسنده , , Anna Maria Almerico، نويسنده , , Gaetano Dattolo، نويسنده , , Girolamo Cirrincione، نويسنده , , Giampietro Viola، نويسنده , , Francesco DallʹAcqua، نويسنده ,
Abstract :
A series of derivatives of the new ring system pyrrolo[2,3-h]quinoline-2-one was synthesized and evaluated as photoreagents toward cultured human tumor cells. Remarkable phototoxycity resulted for some derivatives, especially those bearing the phenyl group at the 7-position.