Title of article
Pyrazolo[4,3-d]pyrimidines as new generation of cyclin-dependent kinase inhibitors
Author/Authors
Daniela Moravcov?، نويسنده , , Vladim?r Kry tof، نويسنده , , Libor Havl? ek، نويسنده , , Ji ? Moravec، نويسنده , , René Lenobel، نويسنده , , Miroslav Strnad، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
2989
To page
2992
Abstract
A search among analogues of anti-CDK purines led to the identification of substituted pyrazolo[4,3-d]pyrimidines as novel inhibitors of CDK1/cyclin B. Some of these derivatives also show antiproliferative activity on cancer cell line K-562, thus may find an application as anticancer agents.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793493
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