Author/Authors :
Zhonghua Pei، نويسنده , , Xiaofeng Li، نويسنده , , Gang Liu، نويسنده , , Cele Abad-Zapatero، نويسنده , , Tom Lubben، نويسنده , , Tianyuan Zhang، نويسنده , , Stephen J. Ballaron، نويسنده , , Charles W. Hutchins، نويسنده , , James M. Trevillyan، نويسنده , , Michael R. Jirousek، نويسنده ,
Abstract :
A salicylate second site binder was linked to three classes of phosphotyrosine mimetics to produce potent protein tyrosine phosphatase 1B (PTP1B) inhibitors which exhibit significant selectivity against other phosphatases including the most homologous member, TCPTP.
