Author/Authors :
Yun He، نويسنده , , Baogen Wu، نويسنده , , Jun Yang، نويسنده , , Dale Robinson، نويسنده , , Lisa Risen، نويسنده , , Ray Ranken، نويسنده , , Lawrence Blyn، نويسنده , , Suzie Sheng، نويسنده , , Eric E. Swayze، نويسنده ,
Abstract :
A series of 2-piperidin-4-yl-benzimidazoles were synthesized and evaluated for antibacterial activities. Certain compounds inhibit bacterial growth with low micromolar minimal inhibitory concentration (MIC). These benzimidazoles are effective against both Gram-positive and Gram-negative bacteria of clinical importance, particularly entercococci, and represent a new class of potential antibacterial agents.
