Title of article
(R)-3-(N-Methylpyrrolidin-2-ylmethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity h5-HT1B/1D ligands
Author/Authors
Ian Egle، نويسنده , , Neil MacLean، نويسنده , , Lidia Demchyshyn، نويسنده , , Louise Edwards، نويسنده , , Abdelmalik Slassi*، نويسنده , , Ashok Tehim، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
3419
To page
3421
Abstract
A series of (R)-3-(N-methylpyrrolidin-2-ylmethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives (2) have been prepared using parallel synthesis, and their structure–activity relationship studied. High affinity human 5-HT1B/1D (h5-HT1B/1D) ligands have been identified.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793580
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