Title of article
Thiadiazole: A new family of intercalative photonuclease with electron transfer and radical mechanisms
Author/Authors
Yonggang Li، نويسنده , , Yufang Xu، نويسنده , , Xuhong Qian، نويسنده , , Baoyuan Qu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
3
From page
3513
To page
3515
Abstract
A new family of photonuclease, thiadiazole-naphthalimide were synthesized and evaluated. Thiadiazole group was incorporated for the first time. These compounds intercalated into DNA efficiently and damaged DNA as low as 10 μM photochemically. Mechanism experiment showed that electron transfer and radicals were involved.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793600
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