Title of article
Novel chromene derivatives as TNF-α inhibitors
Author/Authors
Jie-Fei Cheng، نويسنده , , Akira Ishikawa, Terry L. Wilson، نويسنده , , Yoshinori Ono، نويسنده , , Thomas Arrhenius، نويسنده , , Alex Nadzan، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
3647
To page
3650
Abstract
A novel series of chromene-based TNF-α inhibitors is described. These chromene derivatives inhibit bacterial lipopolysaccharide (LPS) stimulated production of TNF-α from human peripheral blood mononuclear cells (PBMC). Additionally, these compounds inhibit NF-kB mediated transcription activation.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793627
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