Title of article
A novel series of histone deacetylase inhibitors incorporating hetero aromatic ring systems as connection units
Author/Authors
Yujia Dai، نويسنده , , Yan-Guo Wang، نويسنده , , Michael L. Curtin، نويسنده , , Junling Li، نويسنده , , Lori J. Pease، نويسنده , , Jun Guo، نويسنده , , Patrick A. Marcotte، نويسنده , , Keith B. Glaser، نويسنده , , Steven K. Davidsen، نويسنده , , Michael R. Michaelides، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
3817
To page
3820
Abstract
A series of structurally novel HDAC inhibitors, in which a hetero aromatic ring connects the spacer with the hydrophobic group, has been designed and synthesized. These new inhibitors are very potent in in vitro enzymatic assays and display antiproliferation activity against two human cancer cell lines.
Journal title
Bioorganic & Medicinal Chemistry Letters
Serial Year
2003
Journal title
Bioorganic & Medicinal Chemistry Letters
Record number
793665
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